Just a little update about my issue, I think it's strictly related to TorqueLab PostFX system which I noticed it's not working well anymore, I guess there was some changes in the settings and I need to update my script. When I activate the HDR, I get weird result and once I deactivate it, I get the same result as the issue posted above.
Using the standard editor went better but I still got some "Unable to compile shaders" crash when playing with materials.